21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo

21C MUSEUM HOTEL ST LOUIS

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From$234 /night
Check-in
10Jun
Check-out
11Jun
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, 63103
-
Close to the Gateway Arch
Great
8.4
8.8
/10
4.2
4.2
/5

4-star art museum hotel in downtown St Louis

Art & Museum

21C Museum Hotel St Louis is a 4-star property that integrates a contemporary art museum directly into the hotel spaces. The museum on the second floor offers curatorial exhibitions open 24 hours a day at no charge. Guests can explore installations throughout the hotel, including the former YMCA gym and track now used for gallery displays.

Dining

The on-site restaurant Idol Wolf serves Spanish tapas and has been rated among the top three restaurants in the city. Good Press Cafe provides breakfast and gourmet coffee under a restored arched ceiling with original oak paneling. Both dining venues emphasize local ingredients and offer menus available in the bar area as well.

Wellness & Fitness

The hotel houses the Locust Street Athletic Club, a wellness center with a historic indoor lap pool, a large hot tub, a steam room, and a dry sauna. Guests have access to a 24-hour fitness center with yoga classes and a full spa offering massage and wellness packages. Locker rooms with spa facilities are available for guests using the pool and gym.

Rooms & Amenities

Rooms include Deluxe King and Suite categories, each with air conditioning, a seating area, a flat-screen TV, and a private bathroom with free toiletries. The hotel is pet-friendly and offers pet-friendly accommodations upon request. Valet parking is available, and the property provides a 24-hour front desk, concierge service, and luggage storage.

Location & Business

21C Museum Hotel is located in the Downtown St Louis district, within walking distance of the City Museum and a 15-minute walk from the Gateway Arch. The hotel has meeting and event spaces with advanced AV technology, and a business centre with meeting/banquet facilities. Nearby attractions also include Busch Stadium and the Edward Jones Dome.

Highlights

Art: 24/7 free contemporary art museum on site

Dining: Idol Wolf - Spanish tapas restaurant rated top 3 in St Louis

Wellness: Locust Street Athletic Club with historic indoor pool and steam room

Location: 15 min walk to Gateway Arch, near City Museum

Rooms: Pet-friendly accommodations available

Business: Meeting spaces with advanced AV technology

“This hotel truly distinguishes itself with its integrated art museum, a refreshing departure from the typical lodging experience, and the rooms are quite comfortable, with many featuring luxurious soaking tubs and separate showers. The staff, particularly at the valet, consistently go above and beyond, making for an exceptionally accommodating stay. While the valet parking is a necessary expense given the surrounding area, the overall character and quality of the property make it a standout choice.”
Hotel logo
James DavidEditor-in-Chief at Usmissouri

Select your room type

21C Museum Hotel St Louis offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
  • Deluxe King Room
    2 persons
    29 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Deluxe King Suite Roll Shower Accessible
    2 persons
    47 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Loft Two Queen Beds
    2 persons
    40 sq. feet
    2 King Size Beds
    Air conditioning
    Bathtub
Show all rooms

Price and Room Availability Calendar

Check availability and prices for your dates now!
June 2026 - June 2027
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Check-in/ Check-out

Facilities

21C Museum Hotel St Louis offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.7/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
Show more

21C Museum Hotel St Louis Location

1528 Locust Street, Saint Louis, 63103
Explore Saint Louis
Explore St. Louis
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
City Museum
5 minutes walking
A unique playground with art installations, slides, and tunnels-perfect for families and creative minds.
Campbell House Museum
2 minutes walking
An elegant historic home showcasing 19th-century art and furnishings. Complimentary guided tours available.
The Gateway Arch
25 minutes walking
Iconic symbol of St. Louis offering stunning views from the top. Guided tours and free admission days are available.
National Blues Museum
16 minutes walking
Interactive exhibits celebrating blues music's history. Family-friendly with engaging displays and live performances.
Hiking in Lower Meramec Park
15 minutes driving
Scenic park with trails for hiking and picnics. Perfect for nature lovers, with easy access via car.
Yoga at Tower Grove Park
10 minutes driving
Relaxing yoga sessions amidst beautiful nature in the park. Seasonal availability, and mats often provided.
Live Music at The Pageant
15 minutes driving
Renowned venue featuring a variety of live performances from local and national acts. Check the calendar for events.
The Last Kitchen
5 minutes walking
Contemporary American cuisine with locally sourced ingredients. Warm atmosphere and popular brunch specials.
Flannery's
5 minutes walking
Casual Irish pub with a cozy vibe. Signature dishes include hearty stews and a variety of craft beers.
Nara Cafe and Hookah Lounge
4 minutes walking
Chic spot for global cuisine with a vibrant atmosphere. Offers vegetarian options and an extensive tea selection.
Stifel Theatre
8 minutes walking
Historic venue hosting concerts and shows. Check for upcoming events for families and adults alike.
Citygarden Sculpture Park
15 minutes walking
An outdoor park featuring sculptures and water features. A great spot for leisurely strolls or picnics.
Live Jazz at The Dark Room
15 minutes driving
Vibrant venue showcasing local jazz talent. Enjoy cocktails and a relaxed atmosphere in the Delmar Loop.
Getting around
  • City Centre
    Saint Louis 8 min  ·  2000 ft
  • Airports
    Lambert (STL) 33 min  ·  13.5 mi
    MidAmerica St. Louis/Scott Air Force Base (BLV) 62 min  ·  25.4 mi
  • Train
    Union Station 9 min  ·  2300 ft
  • Bus
    Bus stop 3 min  ·  700 ft
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in the entire hotel for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137

Reviews and Ratings

Feedback about 21C Museum Hotel St Louis from previous guests about their experience.
Review score
Based on 1642 verified reviews
8.3 /10
Great
78 %
Recommend
Breakfast
6.6/10
Cleanliness
8.8/10
Comfort
8.7/10
Facilities
8.7/10
Free WiFi
7.7/10
Location
8.6/10
Paid Wi-Fi
5.9/10
Staff
8.6/10
Value for money
8.0/10
Pros
Central location
Unique art concept
Comfortable rooms
Restaurant food
Cons
Valet service issues
Room cleanliness
Guest reviews
based on 1042 reviews
8.4/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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